The apex body of UGC (the Board) consists of eleven members headed by the Executive Chairman. Office bearers are either nominated by the government or invited to act as ex-officio members. Upon the recommendation of the Ministry of Education, the Council of Ministers nominates the Executive Chairman and the Executive Member Secretary of the commission from academic leaders and eminent professors. The secretaries of the Ministry of Education and Ministry of Finance, and a member of National Planning Commission (Social Sector/Education Desk) are the ex-officio members. Among the two Vice-Chancellors represented, one is usually from Tribhuvan University and the other from a different university within Nepal. Two distinguished professors and two prominent educationists are nominated to be members of the apex body. The tenure of the members, including the Chairman and the Member-Secretary, is four years from the date of appointment; however, they are eligible to be reappointed. In order to carry out its duties and responsibilities, UGC had initially set up four divisions: the Administration, Finance, Planning, and Monitoring divisions. With the commencement of the Second Higher Education Project in 2007, Quality Assurance and Accreditation Division, Research Division, HEMIS Section, and Reform Unit have been added to UGC. These divisions and units are headed by officers with expertise and experience in the given areas. The Administration Division is led by a Joint-Secretary Level officer, the Finance Division by an Under-Secretary level finance controller, the Research and Quality Assurance and Accreditation Division by a professor. In addition, UGC occasionally forms different committees and tasks-force units to undertake and fulfill various responsibilities. The University Grants Commission Act specifies provisions for forming different committees and recruiting necessary staff members, hiring service providers, or receiving services of consultants and experts.
UGC has the following committees: ● University Coordination Committee ● Higher Education Reforms Project Steering Committee ● Quality Assurance and Accreditation Committee ● Research Evaluation Committee ● Quality Assurance and Accreditation Technical Committee ● Academic Committee.
In addition to these committees, several other teams, tasks force units, and special task committees, namely the Reform Committee, Cluster Committee, Peer Review Team, Theme/Task Committee, and University Feasibility Study Task Force have also been formed. To create a systematic archive of its activities and achievements, UGC has also formed a publication board which has published historically important documents, research articles, articles on current affairs, and annual reports.